In April 2025, The Guardian reported that Quest Diagnostics used an “alternative reagent” in thousands of urine drug screens conducted within California prisons (https://www.theguardian.com/us-news/2025/apr/09/california-prison-drug-tests). This change, made without sufficient external disclosure, resulted in a dramatic spike in presumptive positive tests for opiates—tripling the usual rate. More than 5,000 incarcerated individuals may have been affected, many …
